While several scholars have examined the foundation and agricultural innovation of the initial 1943 Office of Special Studies (OSS or OEE, the abbreviation in Spanish), this research focuses on, first, the impact of this knowledge on domestic science and rural Mexican development, and, second, the production of agricultural science techniques designed for domestic experimental stations yet implemented beyond Mexico. Consequently, this research examines how these Mexico-based ideas, distinct practices and scientific knowledge looked on the ground in the 1960s when knowledge practices —and seeds—developed in Mexico, arrived in India. In addition to research at the Rockefeller Archive Center (RAC), as well as in national and state archives in Mexico and India, oral histories of farmers and scientists were conducted. This research report briefly examines the sunsetting of the OEE and its fusion into a new, wholly Mexican institute (INIA) which would become vital for later international networks. Simultaneously, the Rockefeller Foundation was expanding its presence in rural India.