In the early twentieth century, Tobacco mosaic virus (TMV) was both an economic problem for tobacco, pepper and tomato growers, and an experimental model system for plant pathologists and virologists. It became the right tool for the job in the first big push to understand the nature of a virus, in particular its constituent chemical components: RNA and coat protein that formed the virus particle. This work, as elaborated by Creager, reveals the intimate links between basic and applied biology and how TMV became a model system for virology, biochemistry, and structural biology between 1935-1960. Today, TMV continues as the right tool and has accumulated several 'firsts'. These include the use of its coat protein trans-gene to mediate protection from subsequent infection by related TMV strains, the biology and mechanism of how TMV spreads from cell to cell using the 30-kilodalton (kDa) movement protein, and the cloning of the TMV N gene from TMV-resistant tobacco followed by the identification of the novel features of the first cloned resistance genes [3-6].
This web page is marked up with Schema.org microdata. Much of the necessary microdata is embedded within the HTML that creates the display you see above. The data that shows below is formatted for machine-reading and rounds out the complete descriptive set for this resource. Want more info about all of this? Go here. You can also view the complete dataset for this resource the way a machine sees it here .
Title: The Development of Plant Virology and Serology in the Early 20th Century
Publication date 2008-01-01
Publication Year 2008
Rockefeller Archive Center
, tobacco mosaic virus
, archives center
Resource provided by IssueLab
IssueLab's Embeddable Widget
Use this super simple form to customize and generate the code you need to display this content in your own environment - no programming required. The feed will inherit more specific styles, like font face and font color, from your website.
Your widget code
Add to the Collection
Please use the form below to provide us with your recommendation, and we'll check it out. Include your name and email address along with your suggestion just in case we need to get in touch. Thank you for contacting us.